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1

Continuous manufacturing: the future in pharmaceutical solid dosage form manufacturing

Desai, Parind Mahendrakumar, Vaerenbergh, Griet Van, Holman, Jim, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

Pharmaceutical Bioprocessing

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

2

Spheronization conditions on spheroid shape and size

Lucy S.C. Wan, Paul W.S. Heng, Celine V. Liew

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 544 KB

english, 1993

3

Understanding die fill variation during mini-tablet production

Goh, Hui Ping, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

4

Development of a visiometric process analyzer for real-time monitoring of bottom spray fluid-bed coating

Celine Valeria Liew, Li Kun Wang, Paul Wan Sia Heng

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

5

Dielectric properties of pharmaceutical materials relevant to microwave processing: Effects of field frequency, material density, and moisture content

Paul W.S. Heng, Z.H. Loh, Celine V. Liew, C.C. Lee

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

6

Understanding disintegrant action by visualization

Parind Mahendrakumar Desai, Celine Valeria Liew, Paul Wan Sia Heng

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 502 KB

english, 2012

7

Spray granulation for drug formulation

Loh, Zhi Hui, Er, Dawn ZL, Chan, Lai Wah, Liew, Celine V, Heng, Paul WS

Journal:

Expert Opinion on Drug Delivery

Year:

2011

Language:

english

File:

PDF, 427 KB

english, 2011

8

Functionality of Disintegrants and Their Mixtures in Enabling Fast Disintegration of Tablets by a Quality by Design Approach

Desai, Parind Mahendrakumar, Er, Patrick Xuan Hua, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

AAPS PharmSciTech

Year:

2014

Language:

english

File:

PDF, 2.98 MB

english, 2014

9

Evaluation of coat uniformity and taste-masking efficiency of irregular-shaped drug particles coated in a modified tangential spray fluidized bed processor

Xu, Min, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

Expert Opinion on Drug Delivery

Year:

2015

Language:

english

File:

PDF, 893 KB

english, 2015

10

Formulation and process strategies to minimize coat damage for compaction of coated pellets in a rotary tablet press: A mechanistic view

Xu, Min, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

11

Review of Disintegrants and the Disintegration Phenomena

Desai, Parind Mahendrakumar, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

12

Influence of the Punch Head Design on the Physical Quality of Tablets Produced in a Rotary Press

Anbalagan, Parthiban, Sarkar, Srimanta, Liew, Celine V., Heng, Paul W.S.

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

13

Powder Flow Testing: Judicious Choice of Test Methods

Tay, Justin Yong Soon, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

AAPS PharmSciTech

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

14

Comparative evaluation of powder flow parameters with reference to particle size and shape

Goh, Hui Ping, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

15

Understanding effects of process parameters and forced feeding on die filling

Goh, Hui Ping, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 2.27 MB

english, 2018

16

The Effects of Feed Frame Parameters and Turret Speed on Mini-Tablet Compression

Goh, Hui Ping, Sia Heng, Paul Wan, Liew, Celine Valeria

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 1.52 MB

english, 2018

17

Insights on the role of excipients and tablet matrix porosity on aspirin stability

Veronica, Natalia, Valeria Liew, Celine, Wan Sia Heng, Paul

Journal:

International Journal of Pharmaceutics

Year:

2020

File:

PDF, 1.65 MB

2020

18

Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum

Michael Piper, Lachlan Harris, Guy Barry, Yee Hsieh Evelyn Heng, Celine Plachez, Richard M. Gronostajski, Linda J. Richards

Journal:

The Journal of Comparative Neurology

Year:

2011

Language:

english

File:

PDF, 5.09 MB

english, 2011

19

Evaluation of sodium alginate as drug release modifier in matrix tablets

Celine Valeria Liew, Lai Wah Chan, Ai Ling Ching, Paul Wan Sia Heng

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 801 KB

english, 2006

20

Layered growth with bottom-spray granulation for spray deposition of drug

Dawn Z.L. Er, Celine V. Liew, Paul W.S. Heng

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

21

Online monitoring of particle mass flow rate in bottom spray fluid bed coating—Development and application

Li Kun Wang, Paul Wan Sia Heng, Celine Valeria Liew

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 431 KB

english, 2010

22

Lama1mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice

Malia M Edwards, D Scott McLeod, Rhonda Grebe, Céline Heng, Olivier Lefebvre, Gerard A Lutty

Journal:

BMC Developmental Biology

Year:

2011

Language:

english

File:

PDF, 2.16 MB

english, 2011

23

A Novel Preformulation Tool to Group Microcrystalline Celluloses Using Artificial Neural Network and Data Clustering

Josephine L. P. Soh, Fei Chen, Celine V. Liew, Daming Shi, Paul W. S. Heng

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

24

Functionality of Cross-Linked Polyvinylpyrrolidone as a Spheronization Aid: A Promising Alternative to Microcrystalline Cellulose

Celine V. Liew, Li Gu, Josephine L. P. Soh, Paul W. S. Heng

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 480 KB

english, 2005

25

Classification of Annular Bed Flow Patterns and Investigation on Their Influence on the Bottom Spray Fluid Bed Coating Process

Li Kun Wang, Paul Wan Sia Heng, Celine Valeria Liew

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 719 KB

english, 2010

26

In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process

Atul D. Karande, Paul Wan Sia Heng, Celine Valeria Liew

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 649 KB

english, 2010

27

Neurogenin 2 controls cortical neuron migration through regulation of Rnd2

Heng, Julian Ik-Tsen, Nguyen, Laurent, Castro, Diogo S., Zimmer, Céline, Wildner, Hendrik, Armant, Olivier, Skowronska-Krawczyk, Dorota, Bedogni, Francesco, Matter, Jean-Marc, Hevner, Robert

Journal:

Year:

2008

Language:

english

File:

PDF, 736 KB

english, 2008

28

Elucidation of spheroid formation with and without the extrusion step

Celine V. Liew, Siang Meng Chua, Paul W. S. Heng

Journal:

AAPS PharmSciTech

Year:

2007

Language:

english

File:

PDF, 1.12 MB

english, 2007

29

Study of coat quality of tablets coated by an on-line supercell coater

Elaine S. K. Tang, Celine V. Liew, Dawn Z. L. Er, Xiaohua Liu, Anthony J. Wigmore, Paul W. S. Heng

Journal:

AAPS PharmSciTech

Year:

2007

Language:

english

File:

PDF, 538 KB

english, 2007

30

Importance of Small Pores in Microcrystalline Cellulose for Controlling Water Distribution during Extrusion–Spheronization

Josephine L. P. Soh, Lei Yang, Celine V. Liew, Fu D. Cui, Paul W. S. Heng

Journal:

AAPS PharmSciTech

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

31

The influence of liquid spray rate and atomizing pressure on the size of spray droplets and spheroids

Lucy S.C. Wan, Paul W.S. Heng, Celine V. Liew

Journal:

International Journal of Pharmaceutics

Year:

1995

Language:

english

File:

PDF, 545 KB

english, 1995

32

Modifying matrix micro-environmental pH to achieve sustained drug release from highly laminating alginate matrices

Ai Ling Ching, Celine Valeria Liew, Lai Wah Chan, Paul Wan Sia Heng

Journal:

European Journal of Pharmaceutical Sciences

Year:

2008

Language:

english

File:

PDF, 765 KB

english, 2008

33

Expression of nuclear factor one A and -B in the olfactory bulb

Céline Plachez, Kathleen Cato, Robert C. McLeay, Yee Hsieh Evelyn Heng, Timothy L. Bailey, Richard M. Gronostasjki, Linda J. Richards, Adam C. Puche, Michael Piper

Journal:

The Journal of Comparative Neurology

Year:

2012

Language:

english

File:

PDF, 2.79 MB

english, 2012

34

Nanocrystalline Brookite with Enhanced Stability and Photocatalytic Activity: Influence of Lanthanum(III) Doping

Perego, Céline, Wang, Yu-heng, Durupthy, Olivier, Cassaignon, Sophie, Revel, Renaud, Jolivet, Jean-Pierre

Journal:

ACS Applied Materials & Interfaces

Year:

2012

Language:

english

File:

PDF, 424 KB

english, 2012

35

Evaluation of the Physicochemical Properties and Compaction Behavior of Melt Granules Produced in Microwave-Induced and Conventional Melt Granulation in a Single Pot High Shear Processor

Z. H. Loh, B. Y. Sia, Paul W. S. Heng, C. C. Lee, Celine V. Liew

Journal:

AAPS PharmSciTech

Year:

2011

Language:

english

File:

PDF, 826 KB

english, 2011

36

Microencapsulation of microbial cells

Rathore, Sweta, Desai, Parind Mahendrakumar, Liew, Celine Valeria, Chan, Lai Wah, Heng, Paul Wan Sia

Journal:

Journal of Food Engineering

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

37

Assessment of disintegration of rapidly disintegrating tablets by a visiometric liquid jet-mediated disintegration apparatus

Desai, Parind M., Liew, Celine V., Heng, Paul W.S.

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 2.07 MB

english, 2013

38

Chick Chorioallantoic Membrane as an In Situ Biological Membrane for Pharmaceutical Formulation Development: A Review

Saw, Constance L. L., Heng, Paul W. S., Liew, Celine V.

Journal:

Drug Development and Industrial Pharmacy

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

39

Distribution of a viscous binder during high shear granulation—Sensitivity to the method of delivery and its impact on product properties

Tan, Bernice Mei Jin, Loh, Zhi Hui, Soh, Josephine Lay Peng, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 813 KB

english, 2014

40

Influence of disintegrants in different substrate physical form on dimensional recovery of multi-component tablet

Sarkar, Srimanta, Ooi, Shing Ming, Liew, Celine Valeria, Tan, Bing Xun, Heng, Paul Wan Sia

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

41

Expression of nuclear factor one A and -B in the olfactory bulb

Plachez, Céline, Cato, Kathleen, McLeay, Robert C., Heng, Yee Hsieh Evelyn, Bailey, Timothy L., Gronostasjki, Richard M., Richards, Linda J., Puche, Adam C., Piper, Michael

Journal:

The Journal of Comparative Neurology

Year:

2014

File:

PDF, 33 KB

2014

42

A prediction model for monitoring ribbed roller compacted ribbons

Quyet, Pham V., Samanta, Asim K., Liew, Celine V., Chan, Lai W., Heng, Paul W. S.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

43

Evaluation of the coat quality of sustained release pellets by individual pellet dissolution methodology

Xu, Min, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

44

New Indices to Characterize Powder Flow Based on Their Avalanching Behavior

Soh, Josephine L. P., Liew, Celine V., Heng, Paul W. S.

Journal:

Pharmaceutical Development and Technology

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

45

Air-dictated bottom spray process: impact of fluid dynamics on granule growth and morphology

Liew, Celine V., Er, Dawn Z.L., Heng, Paul W.S.

Journal:

Drug Development and Industrial Pharmacy

Year:

2009

Language:

english

File:

PDF, 539 KB

english, 2009

46

Insights into the functionality of pelletization aid in pelletization by extrusion-spheronization

Sarkar, Srimanta, Heng, Paul W. S., Liew, Celine V.

Journal:

Pharmaceutical Development and Technology

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

47

Cluster Formation and Drag Reduction-Proposed Mechanism of Particle Recirculation within the Partition Column of the Bottom Spray Fluid-Bed Coater

Wang, Li Kun, Heng, Paul Wan Sia, Liew, Celine Valeria

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

48

Mechanistic Study on Hydration and Drug Release Behavior of Sodium Alginate Compacts

Chan, Lai Wah, Ching, Ai Ling, Liew, Celine Valeria, Heng, Paul Wan Sia

Journal:

Drug Development and Industrial Pharmacy

Year:

2007

Language:

english

File:

PDF, 406 KB

english, 2007

49

Functional role of laminin α1 chain during cerebellum development

Heng, Celine, Lefebvre, Olivier, Klein, Annick, Edwards, Malia, Simon-Assmann, Patricia, Orend, Gertraud, Bagnard, Dominique

Journal:

Cell Adhesion & Migration

Year:

2011

Language:

english

File:

PDF, 7.60 MB

english, 2011

50

Interkinetic nuclear migration

Kulikova, Sofya, Abatis, Marios, Heng, Celine, Lelievre, Vincent

Journal:

Cell Adhesion & Migration

Year:

2011

Language:

english

File:

PDF, 552 KB

english, 2011